Randomized Clinical Trials Of Nonpharmacological Treatments

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Randomized Clinical Trials Of Nonpharmacological Treatments


Randomized Clinical Trials Of Nonpharmacological Treatments
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Randomized Clinical Trials Of Nonpharmacological Treatments


Randomized Clinical Trials Of Nonpharmacological Treatments
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Author : Isabelle Boutron
language : en
Publisher: CRC Press
Release Date : 2011-12-19

Randomized Clinical Trials Of Nonpharmacological Treatments written by Isabelle Boutron and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-19 with Mathematics categories.


Nonpharmacological treatments include a wide variety of treatments such as surgery, technical procedures, implantable and non-implantable devices, rehabilitation, psychotherapy, and behavioral interventions. Unlike pharmacological treatments, these have no specific requirements for approval. Consequently, they can be widely proposed in clinical practice but may not have been adequately evaluated. This situation is an important barrier for the evaluation of the beneficial effects of these treatments and the conduct of clinical trials. Randomized Clinical Trials of Nonpharmacologic Treatments focuses on the methods for assessing nonpharmacological treatments, highlighting specific issues and trial design. Features: Chapters written by international experts in the field Highlights specific issues in assessing nonpharmacological treatments in trials including: how to overcome the difficulties of blinding patients, care providers, and outcome assessors the complexity of the intervention, the learning curve, and the clustering effect placebos that can be used issues of assessing harm and assessing the applicability of trials Presents a variety of trial designs for nonpharmacological treatments—including cluster randomized controlled trials, expertise-based trials, pragmatic trials, and nonrandomized trials. Provides several examples of the planning, conduct, analyses, and reporting of trials in different fields, including surgery, technical interventions, medical devices, rehabilitation, psychotherapy, and behavioral interventions. Providing practical examples that underline these issues and solutions, this book is one of the first to exclusively explore this topic, discussing various categories of treatments, from surgical procedures to psychotherapy.

Randomized Clinical Trials Of Nonpharmacological Treatments


Randomized Clinical Trials Of Nonpharmacological Treatments
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READ ONLINE


Author : Isabelle Boutron
language : en
Publisher: CRC Press
Release Date : 2016-04-19

Randomized Clinical Trials Of Nonpharmacological Treatments written by Isabelle Boutron and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Mathematics categories.


Nonpharmacological treatments include a wide variety of treatments such as surgery, technical procedures, implantable and non-implantable devices, rehabilitation, psychotherapy, and behavioral interventions. Unlike pharmacological treatments, these have no specific requirements for approval. Consequently, they can be widely proposed in clinical practice but may not have been adequately evaluated. This situation is an important barrier for the evaluation of the beneficial effects of these treatments and the conduct of clinical trials. Randomized Clinical Trials of Nonpharmacologic Treatments focuses on the methods for assessing nonpharmacological treatments, highlighting specific issues and trial design. Features: Chapters written by international experts in the field Highlights specific issues in assessing nonpharmacological treatments in trials including: how to overcome the difficulties of blinding patients, care providers, and outcome assessors the complexity of the intervention, the learning curve, and the clustering effect placebos that can be used issues of assessing harm and assessing the applicability of trials Presents a variety of trial designs for nonpharmacological treatments—including cluster randomized controlled trials, expertise-based trials, pragmatic trials, and nonrandomized trials. Provides several examples of the planning, conduct, analyses, and reporting of trials in different fields, including surgery, technical interventions, medical devices, rehabilitation, psychotherapy, and behavioral interventions. Providing practical examples that underline these issues and solutions, this book is one of the first to exclusively explore this topic, discussing various categories of treatments, from surgical procedures to psychotherapy.

Modern Adaptive Randomized Clinical Trials


Modern Adaptive Randomized Clinical Trials
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Author : Oleksandr Sverdlov
language : en
Publisher: CRC Press
Release Date : 2015-06-30

Modern Adaptive Randomized Clinical Trials written by Oleksandr Sverdlov and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-30 with Mathematics categories.


Is adaptive randomization always better than traditional fixed-schedule randomization? Which procedures should be used and under which circumstances? What special considerations are required for adaptive randomized trials? What kind of statistical inference should be used to achieve valid and unbiased treatment comparisons following adaptive random

Pain Management In Special Circumstances


Pain Management In Special Circumstances
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Author : Nabil Shallik
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-11-21

Pain Management In Special Circumstances written by Nabil Shallik and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-21 with Medical categories.


Like management of disease, management of pain is as old as the human race. When patients come to us with their pain, they present us with a wonderful opportunity: the chance to understand them, to understand how their pain is affecting their lives, the challenge of discovering what is causing their pain, and finally the opportunity to prescribe medications and lifestyle changes to help them gain relief from their pain. It is hoped that this book will provide the latest evidence-based updates on pain management in special circumstances and will serve as a ready reference for those embarking on pain management. Its intent is not to be a heavy book that can only be stored on a bookshelf, but a pocket-sized reference that can be carried, be easily navigated, and be available whenever a conceptual gap compromises pain physicians and their ability to treat their patients.

Reducing The Impact Of Dementia In America


Reducing The Impact Of Dementia In America
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Author : National Academies of Sciences Engineering and Medicine
language : en
Publisher:
Release Date : 2022-04-26

Reducing The Impact Of Dementia In America written by National Academies of Sciences Engineering and Medicine and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-26 with categories.


As the largest generation in U.S. history - the population born in the two decades immediately following World War II - enters the age of risk for cognitive impairment, growing numbers of people will experience dementia (including Alzheimer's disease and related dementias). By one estimate, nearly 14 million people in the United States will be living with dementia by 2060. Like other hardships, the experience of living with dementia can bring unexpected moments of intimacy, growth, and compassion, but these diseases also affect people's capacity to work and carry out other activities and alter their relationships with loved ones, friends, and coworkers. Those who live with and care for individuals experiencing these diseases face challenges that include physical and emotional stress, difficult changes and losses in their relationships with life partners, loss of income, and interrupted connections to other activities and friends. From a societal perspective, these diseases place substantial demands on communities and on the institutions and government entities that support people living with dementia and their families, including the health care system, the providers of direct care, and others. Nevertheless, research in the social and behavioral sciences points to possibilities for preventing or slowing the development of dementia and for substantially reducing its social and economic impacts. At the request of the National Institute on Aging of the U.S. Department of Health and Human Services, Reducing the Impact of Dementia in America assesses the contributions of research in the social and behavioral sciences and identifies a research agenda for the coming decade. This report offers a blueprint for the next decade of behavioral and social science research to reduce the negative impact of dementia for America's diverse population. Reducing the Impact of Dementia in America calls for research that addresses the causes and solutions for disparities in both developing dementia and receiving adequate treatment and support. It calls for research that sets goals meaningful not just for scientists but for people living with dementia and those who support them as well. By 2030, an estimated 8.5 million Americans will have Alzheimer's disease and many more will have other forms of dementia. Through identifying priorities social and behavioral science research and recommending ways in which they can be pursued in a coordinated fashion, Reducing the Impact of Dementia in America will help produce research that improves the lives of all those affected by dementia.

Complementary And Alternative Medicine Use Among Adults United States 2002


Complementary And Alternative Medicine Use Among Adults United States 2002
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Author : Patricia M. Barnes
language : en
Publisher:
Release Date : 2004

Complementary And Alternative Medicine Use Among Adults United States 2002 written by Patricia M. Barnes and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Alternative medicine categories.




Non Pharmacological Therapies In The Management Of Osteoarthritis


Non Pharmacological Therapies In The Management Of Osteoarthritis
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Author : Yves Henrotin
language : en
Publisher: Bentham Science Publishers
Release Date : 2012-03-31

Non Pharmacological Therapies In The Management Of Osteoarthritis written by Yves Henrotin and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-31 with Medical categories.


Osteoarthritis is a chronic disease prevalent among the elderly. Its most prominent feature is the progressive destruction of articular cartilage which results in impaired joint motion, severe pain and ultimately disability. Its prevalence and its impact on daily life pose a significant public health problem. Today, a cure for osteoarthritis remains elusive and the management of the disease is largely palliative, focusing on the alleviation of symptoms. Current recommendations include a combination of pharmacological and non-pharmacological treatments. The term “non-pharmacological” includes physical therapy and rehabilitation, but also nutraceuticals. All guidelines on osteoarthritis management highlight the importance of weight loss and physical activity to improve the functional status of patients. A number of alternative therapies are also commonly suggested by physicians and physiotherapists in their daily practice. The efficacy of these therapies is not evidenced by strong clinical trials. This category includes education, information, electrotherapy, ultrasound, electromagnetic field, spa, hydrotherapy, acupuncture, etc. Non Pharmacological Therapies in the Management of Osteoarthritis reviews the clinical relevance of these therapies and the difficulties in conducting high quality trials assessing their efficacy. This e-book presents supportive scientific evidence for their efficacy and explains the mechanism of action of nutraceuticals targeting osteoarthritis. It also includes many example of exercises, mobilization and manipulation techniques directly useful for medical professionals.